Bare, naked fluorescent lights provide strong, white light that can be too glaring at times, particularly depending on how the light spills onto the space. With a few minor, inexpensive changes to a diffuser panel, you can soften the light and even add some drama to the room. Fluorescent lights can be on the ceiling, on a wall or on the floor, so there are different methods of creating an effective diffuser panel that is also pleasing to the eye.
Replace your current plain acrylic diffuser with textured glass, stained glass, etched glass or alabaster tile. This alternative works especially well if the fluorescent light is a ceiling light. Opaque white textured glass or alabaster creates the softest glow with the brightest light; etched glass has pockets of very bright light and "barely-there" light, depending on how much etching was used; colored or stained glass diffuses your light the most, and casts interesting colored shadows that give a semblance of drama and mystery to an otherwise bland space.
Modify a long rectangular wooden planter hedge box--a good alternative if the fluorescent light is mounted on a wall. Remove one long panel for light to be upwardly directed, creating a diffused glow; remove one long panel and the bottom panel for light diffusion upward and downward. Attach the box over the light with strong glue or L-shaped brackets; it should look like a long sconce.
Enhance your acrylic panel diffuser; trace a stencil over contact paper, cut out the pattern with a craft knife and attach to the inner panel. Paint the whole panel with watercolor; when dry, peel off the contact paper. Watercolor is translucent and allows some light through, creating a diffused glow.
Use glass blocks with any interesting pattern and color of your choice over a floor light source (clubs, executive suite hallways, upscale homes). Glass tiles are not a safe option where feet can kick in a crack.