What Household Chemicals Can Cause a Chemical Reaction?

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Bleach reacts with a variety of other chemicals around the house.

It's important to know the properties of household cleaning chemicals before you try to mix them. Some household cleaning agents are more or less harmless, while others can react to release toxic gases when combined. Vinegar and baking soda, for example, won't cause you any harm. A mixture of ammonia and bleach, on the other hand, is a different matter.

Bleach and Acid

Bleach is a strongly alkaline solution that reacts with acids, such as those found in many tile and toilet bowl cleaners, to generate chlorine gas, which quickly bubbles out of the solution. Chlorine was used as poison gas during World War I, and it's definitely not something you want to have around. Bleach can react with vinegar as well to release chlorine gas, although in this case far less is produced since vinegar is a weaker and less concentrated acid.

Acid, Ammonia and Sodium Hydroxide

Acids such as those found in tile or toilet bowl cleaners, vinegar and lemon juice can react with ammonia and sodium hydroxide, both of which are basic. Ammonia solutions will undergo a neutralization reaction with an acid; vinegar and ammonia, for example, form ammonium acetate. Sodium hydroxide is a much stronger base found in some oven cleaners and most drain openers. It too reacts with acids, but the reaction here is more violent and can release a considerable amount of heat. Ammonia and bleach also will react to release a cocktail of toxic gases, including several chloramine compounds and even hydrazine (a compound often used to make rocket fuel). That's why mixing ammonia and bleach at home is never a good idea.

Baking Soda and Acid

Mixing baking soda with an acid such as lemon juice, vinegar or hydrochloric acid from pool supplies will cause an acid-base neutralization, much like the ammonia and the vinegar. An acid-base neutralization with sodium bicarbonate, however, nearly always releases a large amount of carbon dioxide bubbles. As the concentration of carbonic acid in the solution increases, it decomposes to CO2 and water, and the solution bubbles furiously. Hydrogen peroxide also can cause a somewhat violent reaction when combined with chlorine bleach.


Among the most dangerous chemical reactions you can have in your household are those involving flammable chemicals. Acetone is highly volatile, and at sufficient concentrations, its vapor can be ignited by heat or spark and start combustion (which is, after all, a chemical reaction). Many nail polish removers contain acetone. Chemicals such as the ethanol in liquor and the isopropanol in rubbing alcohol are also flammable, although they are typically diluted with water and hence difficult to burn. Natural gas and propane, of course, are also highly flammable.


John Brennan

Based in San Diego, John Brennan has been writing about science and the environment since 2006. His articles have appeared in "Plenty," "San Diego Reader," "Santa Barbara Independent" and "East Bay Monthly." Brennan holds a Bachelor of Science in biology from the University of California, San Diego.