Permanent marker stains from Sharpies can be difficult to remove, in some cases impossible. That said, if you work fast you may be able to get a Sharpie stain off bed sheets and clothing with the correct stain removal process and products.
Step 1
Sponge the stain with rubbing alcohol until it is completely moistened.
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Step 2
Dab the stain with a wad of clean, damp paper towels. The color from the permanent marker should be transferring to the paper towel. Keep repeating the process until the stain is gone.
Step 3
Apply denatured alcohol to the stain if the stain does not lift with the rubbing alcohol. Apply the denatured alcohol with cotton swabs for a more precise application.
Step 4
Blot the spot with clean, damp paper towels again. The color from the Sharpie should transfer to the paper towels.
Step 5
Dip a cotton swab in acetone nail polish remover. Swab the marker spot with the nail polish remover. This should help fade the rest of the marker.
Step 6
Wipe up the nail polish remover with moistened paper towels. If the stain is gone, launder the item as usual.