Permanent marker stains left behind on a shirt can remain on the clothing forever if you do not treat the stain immediately. The marker leaves behind fade-resistant marks that can become a challenge to remove. If you notice a permanent stain on your shirt left behind by a Sharpie marker, you can treat the stain with items you have around your home. You may have to treat the stain several times to remove it completely from your shirt.
Place the shirt on a flat surface, face down, onto paper towels.
Soak a cotton ball with rubbing alcohol.
Blot the underside of the marker stain with the alcohol-soaked cotton ball. You will need to open up the shirt from the bottom and place the cotton ball directly behind the stain, or the stain may transfer to the back of the shirt.
Replace the paper towels once they are soaked with the ink. Continue to blot the stain with the rubbing alcohol until it no longer transfers onto the paper towels.
Place the shirt into the laundry machine. Launder it according to the care label.
Remove the shirt from the laundry machine. If you notice the ink stain remains, repeat the process until it disappears. Hang the shirt to dry to ensure that you removed the Sharpie ink completely, because a dryer will cause the stain to become permanent.