Sharpie markers are generally considered to be permanent markers. While it is true that the ink from these markers is resistant to most stain-removal methods, you can remove Sharpie marks from certain surfaces. If you accumulate Sharpie ink stains on your computer keyboard, for instance, you can remove these marks using inexpensive items that you may already have right at home.
Unplug the keyboard from your computer.
Cover the Sharpie ink stains with ink from a dry-erase marker.
Wipe off the dry-erase marker with a clean, dry, soft cloth. The permanent ink will come off as well.
Plug the keyboard back in to your computer.