A glass of wine with dinner is lovely, unless it ends up on your furniture. Wine is an acidic stain that sets quickly and leaves discoloration that can last a lifetime unless you act quickly. Your first line of defense is cold water. For easiest removal, the stain should remain wet if it is fresh. Further cleaning with cleaners will remove the remainder of the color and odor. Microfiber fabrics are good for repelling moist liquids, but when wine gets into the fabric, you need more than soap and water to completely remove it.
Pour salt onto very fresh stains. This will soak up much of the liquid and keep the stain from setting. Vacuum up the salt or shake it off. Blot the stain with cold water to get out as much wine as possible.
Pour 2 or 3 drops of liquid dish detergent and 1/2 cup of white vinegar into a bowl. Dip a rag into the mixture, and use it to scrub the stain. Scrub both sides of the article if you can. Allow the mixture to sit on the stain five minutes, then dampen a clean rag and use it to blot up the stain. Rinse and repeat until the stain is lifted. Microfiber will wick away some water initially, so you need to really saturate the site to begin to lift out the wine.
Blot any stain that remains with dry-cleaning solvent. Moisten a corner of a clean rag, and press it into the microfiber until it begins to penetrate the natural wicking properties of the cloth, then rub lightly across the fabric. Change spots on the rag frequently, rewetting with solvent, and rubbing until no stain remains.
Make a paste of oxygen bleach or detergent mixed with hydrogen peroxide. Blot the paste onto the stain, and allow it to work for five minutes. Blot with a clean rag and fresh water until it has been removed.
Soak a red wine stain in white wine. The white wine keeps the red from setting. Then make a paste of baking soda and water. Press the paste into the stain. Let it penetrate and work for a few hours, moistening it with water as it starts to dry out. Rinse off the paste.
Use alcohol wipes to remove the bleed marks from microfiber from a white wine spill. Press the wipes into the stain, and feather out the edges with the moist wipes. White wine stains leave a water ring and odor, which baking soda paste will help remove. Use the baking soda and water paste after removing the moisture ring on the microfiber couch.