Fire ants can be a real garden nuisance, and to make matters worse, when agitated, they bite. If you're not interested in using garden chemicals, there are a number of natural alternatives you can use to get rid of them.
Do your gardening homework to make sure that the plants around the anthill will not be damaged by the vinegar before spraying. Some plants are more sensitive than others.
Fill a spray bottle with a mixture of two parts vinegar and one part water. Shake the bottle to ensure that the vinegar and water is mixed well.
Spray the ant mound as often as necessary and monitor the ant behavior, and to ensure that they are dying off.
Pour pure vinegar on stubborn mounds if the ants don't die, or relocate and create new mounds. Use 1/4 cup of undiluted vinegar twice daily.
Monitor the progress to ensure that the vinegar method is working. If it does not work, try alternative liquids. Citrus juice, like pure lemon juice is one alternative.