Getting rid of mice can be challenging, but it is possible to use homemade methods to clear your home of unwanted pests. All methods of mouse removal require patience and diligence, but some are more efficient than others. First you must prevent mice from entering your home, and then you must kill or trap and remove them.
Eliminate Food Sources and Points of Entry
Keep all food in tightly sealed metal or glass canisters. Keep trash in lidded, thick containers. Keep counter tops and floors clean. Do not leave food out unattended and clean up crumbs.
Seal all possible points of entry into your home. Inspect your home for cracks and crevices, and seal them with steel wool, concrete or wire mesh. A mouse can enter your home through a hole as small as a pencil eraser.
Keep firewood at least 18 inches off the ground and away from all buildings. Plant bushes and gardens 3 inches away from the house. Trim overhanging branches with garden shears. Do not leave pet food outside and put bird feeders on a pole so rats and mice cannot access the seed.
Create simple mouse traps and bait them with a cotton ball spread with peanut butter or a small piece of bacon. Fill a 5-gallon bucket with water and a little dish soap until it is a least two thirds of the way full. Rest a long piece of wood on the rim of the bucket. One end of the wood should touch the floor while the other should be at the top of the bucket. Leave bait on the ramp and in the water. Check the trap in the morning for drowned mice.
Form cardboard or plastic into a long tube shape to create a humane trap. The tube should have the same diameter as a toilet paper tube. Place the tube on a table so that one quarter of the tube is on the table and the rest is hanging off the end. Place a tall, heavy bucket directly below where the tube hangs over the table. Place some bait in front of the tube. Take care not to get bitten when cleaning traps. Wear heavy leather gloves and handle the trap opposite from the rodent's head.
Get a cat or dog. They are great rodent killers. Make sure your neighbors are not using rodent poison as this can hurt your pet.